硕士生导师、副教授、博士;手机:13891690861;E-mail:liuxiang888525@163.com
个人简历:刘祥,男,1983年生,副教授,硕士生导师,中山大学生化与分子专业博士,西北农林科技大学兽医学博士后,德国柏林自由大学访学,安徽省生物化学与分子生物学学会理事,主要从事动物疫苗研究。主持科技部高端外国专家项目1项、陕西省科技厅重点研发、面上项目各1项,主持教育厅项目3项、校级项目4项、横向项目2项。参与国家高技术研究发展(863)计划、国家自然科学基金、国家高端外专局项目、陕西省科技厅重点研发、陕西省科技创新团队等项目8项。以第一作者/通讯作者在Vaccines、J Proteome Res、Fish Shellfish Immunology等国内外知名期刊上发表论文40余篇,其中SCI收录14篇。Vaccines、Applied Microbiology and Biotechnology、Biomed Research International、Journal of Medicinal Food、Journal of Cellular Biochemistry等期刊审稿人。申请国家发明专利3项,参与出版专著1部;获校级优秀硕士生导师、优秀科技工作者、优秀本科生指导教师、优秀班主任称号。指导研究生获国家奖学金2人次,校优秀毕业论文、校优秀毕业生各1次;指导本科生获国家级大学生创新创业项目1项、省级2项,指导本科生获“大学生挑战杯科技论文竞赛”省二等奖1次。
(1)主要承担科研项目
①陕西省科技厅基础研究计划面上项目:基于表位疫苗技术的奶山羊乳房炎多价疫苗的合成及免疫机制研究(2022JM-120),2022年,主持,5万元,在研。
②科技部国家外国专家局项目:秦岭特色生物资源开发利用关键技术研究与示范(GDT20186100426),2018年,主持,32万元,已结题。
③陕西省教育厅科学研究计划项目:奶牛乳房炎三联表位多肽疫苗的研制及免疫保护功能研究(17JK0137),主持,2017年,2万元,已结题。
④陕西省科技厅重点研发项目:奶牛乳房炎三联重组表位多肽疫苗的研发(2016NY-088),2016年,主持,10万元,已结题。
⑤陕西省教育厅科学研究计划项目:骨硬化蛋白在股骨头坏死症中的作用研究(2013JK0723),2013年,主持,2万元,已结题。
(2)代表性科研论文
①Liu Xiang, Rong Na, Sun Wei, et al. The identification of polyvalent protective immunogens and immune abilities from the outer membrane proteins ofAeromonas hydrophilain fish. Fish & Shellfifish Immunology, 2022, 128: 101-122.(IF= 4.622,一区)
②Liu Xiang, Sun Wei, Jian Sijie, et al. Synthesis ofEscherichia coliOmpA oral nanoparticles and evaluation of immune functions against the major etiologic agent of cow mastitis. Vaccines, 2021, 9: 304.(IF= 4.961,二区)
③Liu Xiang, Sun Wei, Jian Sijie, et al. Passive protective ability of the outer membrane protein PF1380 ofPseudomonas fluorescensagainst the major pathogenic bacteria of freshwater aquaculture in fish. Aquaculture Reports, 2022, 22: 100985.(IF= 3.38,二区)
④Liu Xiang, Yang Manjun, Wang Shengnan, et al. Difffferential antibody responses to outer membrane proteins contribute to difffferential immune protections between live and inactivatedVibrio parahemolyticus. Journal of Proteome Research, 2018, 17: 2987-2994.(IF= 5.37,二区)
⑤Sun Wei, Rong Na, Jian Sijie, Kang Chao, Chen Chunlin, Chen Rui, Ding Rui, Chen Chen,Liu Xiang*.Immune responses and protective efficacy of outer membrane protein ExbB ofPseudomonas fuorescensagainstAeromonas hydrophilaandPseudomonas fuorescensaffectingCarassius auratus. Aquaculture International, 2021, 29:2823-2840.(通讯作者,IF=2.953,三区)
⑥Liu Xiang, Chen Chen, Zhang Xiaoying. Drug–drug interaction of acetaminophen and roxithromycin with the cocktail of cytochrome P450 and hepatotoxicity in rats. International Journal of Medical Sciences, 2020, 17: 414-421.(IF= 3.738,三区)
⑦Xu Long,Liu Xiang*, Chen Chen, et al. Determination of dehydroepiandrosterone in dietary supplements and pharmaceutical products by a competitive chemiluminescent enzyme immunoassay. Analytical Letters, 2020, 3: 842-853. (通讯作者, IF=2.329,四区)
⑧Chen Chen, …Liu Xiang*, Zhang Xiaoying. Immunoprotective evaluation ofEscherichia coliouter membrane protein A against the main pathogens of animal mastitis. Tropical Journal of Pharmaceutical Research January, 2020, 19 (1): 155-162. (通讯作者, IF= 0.533,四区)
⑨Chen Chen, …Liu Xiang*, Zhang Xiaoying*. Purification and characterization of lysozyme from Chinese Lueyang black-bone Silky fowl egg white. Preparative Biochemistry & Biotechnology, 2019, 49(3): 215-221. (通讯作者, IF= 2.162,四区)
⑩Chen Chen, …Zhang Xiaoying,Liu Xiang*. Evaluation of immunogenicity, protective immunity on aquaculture pathogenicVibrioand fermentation ofVibrio alginolyticusflagellin FlaC protein. Iranian Journal of Biotechnology, 2019, 17(3): e2628. (通讯作者, IF= 0.973,四区)
⑪Chen Chen, …Liu Xiang*, Zhang Xiaoying*. Purification and characterization of an antimicrobial protein fromGastrodia elata Blumetubers. Tropical Journal of Pharmaceutical Research, 2018, 17(9): 1717-1723. (通讯作者, IF= 0.533,四区)
⑫Liu Xiang, Chen Chunlin, Chen Chen, et al. Construction of a recombinant OmpC dominant epitope based vaccine againstEscherichia coli and evaluation of its immunogenicity and protective immunity. Jundishapur Journal of Microbiology, 2017, 10(11):e55652. (IF= 1.233,四区)
⑬Liu Xiang, Chen Chunlin, Chen Chen, et al. Construction and evaluation of a novel triple cell epitope based polypeptide vaccine against cow mastitis induced byStaphylococcus aureus,Escherichia coliandStreptococcus. Tropical Journal of Pharmaceutical Research, 2017, 16 (10): 2477-2486. (IF= 0.533,四区)
⑭Liu Xiang, She Xintao, Zhu Qingfeng, et al. Heterogeneous interactome betweenLitopenaeus vannameiplasma proteins andVibrio parahaemolyticusouter membrane proteins. Fish & Shellfifish Immunology, 2013, 34: 192-198.(IF= 4.622,一区)